1. Kambayashi D, Manabe T, Hirohara M. Adaptations in the role of pharmacists under the conditions of the COVID-19 pandemic: a systematic review and meta-analysis. BMC Health Serv Res. 2023 Jan 24;23(1):72. doi: 10.1186/s12913-023-09071-w.
  2. Otani K, Watanabe T, Higashimori A, Suzuki H, Kamiya T, Shiotani A, Sugimoto M, Nagahara A, Fukudo S, Motoya S, Yamaguchi S, Zhu Q, Chan FKL, Hahm KB, Tablante MC, Prachayakul V, Abdullah M, Arg TL, Murakami K. A questionnaire-based survey on the impact of COVID-19 pandemic on gastrointestinal endoscopy in Asia. Digestion. 2022; 103: 7-21. doi: 10.1159/000520287. 
  3. Uruma Y, Manabe T, Fujikura Y, Iikura M, Hojo M, Kudo K. Effect of asthma, COPD, and ACO on COVID-19: A systematic review and meta-analysis. PLOS ONE. 2022;17(11):e0276774. doi: 10.1371/journal.pone.0276774.
  4. Nohara Y and Manabe T. Impact of human mobility and networking on spread of COVID-19 at the time of the 1st and 2nd epidemic waves in Japan: an effective distance approach. PLOS ONE. 2022;17(8):e0272996. doi: 10.1371/journal.pone.0272996.
  5. Kambayashi D, Manabe T, Hirohara M, Akatsu H. Knowledge, Attitudes, and Practices Survey among Nursing Care Workers Involved in Caring for Older Adults during the Early Stage of the COVID-19 Pandemic in Japan. Int J Environ Res Public Health 2022;19(20):12993. doi: 10.3390/ijerph192012993.
  6. Nakayama H, Ogawa C, Sekimizu M, Fujisaki H, Kosaka Y, Hashimoto H, Saito AM, Horibe K. A Phase I Study of Inotuzumab Ozogamicin as a Single Agent in Pediatric Patients in Japan with Relapsed/Refractory CD22-Positive Acute Lymphoblastic Leukemia (INO-Ped-ALL-1). Int J Hematol. 2022;116:612-621.
  7. Ito K, Kanemitsu Y, Kamiya T, Fukumitsu K, Takeda N, Tajiri T, Kurokawa R, Nishiyama H, Yap J, Fukuda S, Uemura T, Okubo H, Maeno K, Ito Y, Oguri T, Takemura M, Niimi A. Functional gastrointestinal disorders are associated with capsaicin cough sensitivity in severe asthma. Allergol Int. 2022; S1323
    doi: 10.1016/j.alit.2022.08.009.
  8. Fukuta H, Hagiwara H, Kamiya T. Sodium-glucose cotransporter 2 inhibitors in heart failure with preserved ejection fraction: A meta-analysis of randomized controlled trials. Int J Cardiol Heart Vasc. 2022;42:101103.
  9. Manabe N, Joh T, Higuchi K, Iwakiri K, Kamiya T, Haruma K, Nakada K. Clinical significance of gastroesophageal reflux disease with minimal change: a multicenter prospective observational study. Sci Rep. 2022; 12: 15036.doi: 10.1038/s41598-022-19408-w.
  10. Hashimoto H, Kada A. A Note on Confidence Intervals for the Restricted Mean Survival Time Based on Transformations in Small Sample Size. Pharm Stat. 2022;21:309-316.
  11. Manabe T, Masaki Y, Yamamoto Y, Yamamoto K, Kohashi O, Yamamoto T, Ohara H, Akatsu H. Association of nutritional support with survival-time in hospitalized older patients with dysphagia: a retrospective study. Ann Nutr Metab.2022. doi: 10.1159/000524085.
  12. Akatsu H, Manabe T, Kawade Y, Masaki Y, Hoshino S, Jo T, Kobayashi S, Hayakawa T, Ohara H. Effect of Ankle Weights as a Frailty Prevention Strategy in the Community-Dwelling Elderly: A Preliminary Report. Int J Environ Res Public Health 2022;19(12):7350. doi: 10.3390/ijerph19127350.
  13. Kumagai K, Murotsuki J, Dohi S, Nishikawa N, Kimura N, Nomiyama M, Osaga S, Hashimoto H, Nakai A, Ogasawara MS, Ozaki Y. Does a cervical pessary reduce the rate of preterm birth in women with a short cervix? J Perinat Med. 2022;50:1107-1114.
  14. Matsumura T, Hashimoto H, Sekimizu M, Saito AM, Motoyoshi Y, Nakamura A, Kuru S, Fukudome T, Segawa K, Takahashi T, Tamura T, Komori T, Watanabe C, Asakura M, Kimura K, Iwata Y. Tranilast for advanced heart failure in patients with muscular dystrophy: A single-arm, open-label, multicenter study. Orphanet J Rare Dis. 2022;17:201. 
  15. Kamiya T, Fukuta H, Hagiwara H, Shikano M, Kato T, Imaeda K. Disturbed gastric motility in patients with long standing diabetes mellitus.
    J Smooth Muscle Res. 2022; 58: 1-10. doi: 10.1540/jsmr.58.1.
  16. Kida D, Hashimoto H, Saito AM, Kito Y, Hattori Y, Terabe K, Mori K, Takahashi N, Tomita Y. The efficacy and safety of a novel extramedullary guide coordinated with 3D surgical assistive software for total knee arthroplasty: an open-label single-arm trial. Kurume Med J. 2022 Mar 11;67(1):31-40. doi: 10.2739/kurumemedj.MS671002.
  17. Suzuki N, Okuyama T, Akechi T, Kusumoto S, Ri M, Inagaki A, Kayukawa S, Yano H, Yoshida T, Shiraga K, Hashimoto H, Aiki S, Iida S. Symptoms and health-related quality of life in patients with newly diagnosed multiple myeloma: a multi-center prospective cohort study. Jpn J Clin Oncol. 2022;52:163-169. 
  18. Goto T, Nakayama T, Yamamoto J, Mori K, Shintani Y, Kikuchi S, Fujita H, Fukuta H, Seo Y. Reclassification of Heart Failure with Preserved Ejection Fraction Following Cardiac Sympathetic Nervous System Activation: A New Cutoff Value of 58. Tomography. 2022 ;8:1595-1607.
  19. Fukuta H, Goto T, Wakami K, Kamiya T, Ohte N. Effects of catheter-based renal denervation on heart failure with reduced ejection fraction: a meta-analysis of randomized controlled trials. Heart Fail Rev. 2022;27:29-36.



  1. Kogure Y, Iwasawa S, Saka H, Hamamoto Y, Kada A, Hashimoto H, Atagi S, Takiguchi Y, Ebi N, Inoue A, Kurata T, Okamoto I, Yamaguchi M, Harada T, Seike M, Ando M, Saito AM, Kubota K, Takenoyama M, Seto T, Yamamoto N, Gemma A. Efficacy and safety of carboplatin with nab-paclitaxel versus docetaxel in elderly patients with squamous-cell lung cancer (CAPITAL): A randomized, multicenter, openlabel, Phase 3 trial. Lancet Healthy Longev. 2021;2:e791-e800.
  2. Okamoto R, Manabe T, Mizukami K. Effects of Facial Muscles Exercise on Mental Health: A Systematic Review. Int J Environ Res Public Health. 2021;18(22):12216. doi: 10.3390/ijerph182212216. PMID: 34831972; PMCID: PMC8623932.
  3. Kogure Y, Hashimoto H, Oki M. A Randomized Phase III Study of Pembrolizumab versus Pembrolizumab-Carboplatin-Pemetrexed for Locally Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer with PD-L1 50% or more (LAPLACE-50): Study Protocol, Clin Lung Cancer. 2021;22:e921-e924.
  4. Goto T, Mori K, Nakayama T, Yamamoto J, Shintani Y, Wakami K, Fukuta H, Seo Y, Ohte N. Multimorbidity, polypharmacy, and mortality in older patients with pacemakers. J Arrhythm. 2021;38:145-154.
  5. Manabe T, Phan D, Nohara Y, Kambayashi D, Nguyen TH, Van Do T, Kudo K. Spatiotemporal distribution of COVID-19 during the first 7 months of the epidemic in Vietnam. BMC Infect Dis. 2021;21(1):1124. doi: 10.1186/s12879-021-06822-0. PMID: 34717588; PMCID: PMC8556820.
  6. Kambayashi D, Manabe T, Kawade Y, Hirohara M. Knowledge, attitudes, and practices regarding COVID-19 among pharmacists partnering with community residents: A national survey in Japan. PLOS ONE 2021;16(10):e0258805. doi: 10.1371/journal.pone.0258805.
  7. Matsumura T, Takada H, Kobayashi M, Nakajima T, Ogata K, Nakamura A, Funato M, Kuru S, Komai K, Futamura N, Adachi Y, Arahata H, Fukudome T, Ishizaki M, Suwazono S, Aoki M, Matsuura T, Takahashi MP, Sunada Y, Hanayama K, Hashimoto H, Nakamura H. A Web-based questionnaire survey on the influence of coronavirus disease-19 on the care of patients with muscular dystrophy. Neuromuscul Disord. 2021;31:839-846.
  8. Banno T, Wakami K, Kikuchi S, Fujita H, Goto T, Fukuta H, Seo Y, Ohte N. Non-Invasive Estimation of Left Ventricular Filling Pressure Based on Left Atrial Area Strain Measured With Transthoracic 3-Dimensional Speckle Tracking Echocardiography in Patients With Coronary Artery Disease. Circ Rep. 2021;3:520-529.
  9. Muto K, Wakami K, Yamamoto J, Banno T, Kikuchi S, Goto T, Fukuta H, Seo Y, Ohte N. Correlation Between Longitudinal Strain in the Apical Segments of the Left Ventricle at End-Systole Obtained by 2-Dimensional Speckle-Tracking Echocardiography and Left Ventricular Relaxation. Circ J. 2021;85:1575-1583.
  10. Osaga S, Nakada K, Iwakiri K, Haruma K, Joh T, Kamiya T. Sex differences in risk factors for future onset of reflux esophagitis. J Clin Biochem Nutr. 2021; 69: 91-97. doi: 10.3164/jcbn.20-202.
  11. Goto T, Kikuchi S, Mori K, Nakayama T, Fukuta H, Seo Y, Narita H, Iida A, Ohte N. Cardiac β-Adrenergic Receptor Downregulation, Evaluated by Cardiac PET, in Chronotropic Incompetence. J Nucl Med. 2021;62:996-998.
  12. Manabe T, Kambayashi D, Akatsu H, Kudo K. Favipiravir for the treatment of patients with COVID-19: A systematic review and meta-analysis. BMC Infect Dis. 2021; 21(1):489. doi: 10.1186/s12879-021-06164-x.
  13. Hagiwara H, Fukuta H, Hashimoto H, Niimura T, Zamami Y, Ishizawa K, Kamiya T, Ohte N. A comparison of the safety and effectiveness of prasugrel and clopidogrel in younger population undergoing percutaneous coronary intervention: A retrospective study using a Japanese claims database.
    J Cardiol. 2021; 77: 285-291.
  14. Ogawa M, Arihiro S, Matsuhashi N, Joh T, Higuchi K, Iwakiri K, Kamiya T, Manabe N, Isshi K, Nakada T, Hokari A, Saruta M, Oshio A, Haruma K, Nakada K. The early therapeutic response at 2 weeks is a crucial predictor of proton pump inhibitor-refractory gastroesophageal reflux disease. Esophagus. 2021; 18: 398-406. doi: 10.1007/s10388-020-00792-z.
  15. Fukudo S, Okumura T, Inamori M, Okuyama Y, Kanazawa M, Kamiya T, Sato K, Shiotani A, Naito Y, Fujikawa Y, Hokari R, Masaoka T, Fujimoto K, Kaneko H, Torii A, Matsueda K, Miwa H, Enomoto N, Shimosegawa T, Koike K.
    Evidence-based clinical practice guidelines for irritable bowel syndrome 2020. J Gastroenterol. 2021; 56:193-217. doi: 10.1007/s00535-020-01746-z.
  16. Kamiya T, Osaga S, Kubota E, Fukudo S, Motoya S, Murakami K, Nagahara A, Shiotani A, Sugimoto M, Suzuki H, Watanabe T, Yamaguchi S, Chan FKL, Hahm KB, Fock KM, Zhu Q; International Gastroenterology Consensus Symposium Study Group. Questionnaire-based survey on epidemiology of functional gastrointestinal disorders and current status of gastrointestinal motility testing in Asia countries. Digestion. 2020;102: 73-89.doi:10. 1159/000513292
  17. Fukuta H, Goto T, Wakami K, Kamiya T, Ohte N. Effect of beta-blockers on heart failure severity in patients with heart failure with preserved ejection fraction: a meta-analysis of randomized controlled trials. Heart Fail Rev. 2021;26:165-171



  1. Mori H, Schol J, Geeraerts A, Huang IH, Jandee S, Gonlachanvit S, Tseng PH, Lu CL, Kamiya T, Kim N, Lee YY, Kuribayashi S, Tack J. The impact of COVID-19 on gastrointestinal motility testing in Asia and Europe. J Clin Med. 2020; 9: 3189. doi: 10.3390/jcm9103189.
  2. Kawada S, Futamura M, Hashimoto H, Ono M, Akita N, Sekimizu M, Hattori H, Goto M, Horibe K, Maeda N. Association between sites and severity of eczema and the onset of cow’s milk and egg allergy in children. PLoS One. 2020;15: e0240980.
  3. Manabe T, Akatsu H, Kotani K, Kudo K. Trends in clinical features of novel coronavirus disease (COVID-19): A systematic review and meta-analysis of studies published from December 2019 to February 2020. Respiratory Investigation 2020;58(5):409-418. doi: 10.1016/j.resinv.2020.05.005.
  4. Akatsu H, Manabe T, Kawade Y, Tanaka H, Kanematsu T, Arakawa K, Masaki Y, Hishida C, Kanesaka T, Ogawa N, Hashizume Y, Tsuneyama K, Ohara H, Maruyama M, Yamamoto T. Iron deposition in autopsied liver specimens from older patients receiving intravenous iron infusion. PLOS ONE 2020;15(8):e0237104.
  5. Manabe T, Kotani K, Teraura H, Minami K, Kohro T, Matsumura M. Characteristic Factors of Aspiration Pneumonia to Distinguish from Community-Acquired Pneumonia among Oldest-Old Patients in Primary-Care Settings of Japan. Geriatrics (Basel) 2020;5(3):42. doi: 10.3390/geriatrics5030042. PMID: 32645839; PMCID: PMC7555817.
  6. Isshi K, Matsuhashi N, Joh T, Higuchi K, Iwakiri K, Kamiya T, Manabe N, Nakada T, Ogawa M, Arihiro S, Haruma K, Nakada K. Clinical features and therapeutic responses to proton pump inhibitor in patients with severe reflux esophagitis: A multicenter prospective observational study. JGH Open. 2020; 5: 99-106. doi: 10.1002/jgh3.12455.
  7. Hojo M, Nagahara A, Hahm KB, Iwakiri R, Watanabe T, Rani AA, Zhu Q, Chan FKL, Sollano JD, Kamiya T, Yamaguchi S, Motoya S, Fock KM, Fukudo S, Kachintorn U, Suzuki H, Murakami K. Management of gastroesophageal reflux disease in Asia countries: results of a questionnaire survey. Digestion. 2020; 101: 66-79. doi: 10.1159/000504749.
  8. Goto T, Mori K, Nakayama T, Yamamoto J, Shintani Y, Nakasuka K, Wakami K, Fukuta H, Seo Y, Ohte N. Transmission Rate of Remote Monitoring and Mortality in Patients With Pacemaker. Circ Rep. 2020;2:471-478.
  9. Takeda N, Takemura M, Kanemitsu Y, Hijikata H, Fukumitsu K, Asano T, Yamaba Y, Suzuki M, Kubota E, Kamiya T, Ueda T, Niimi A. Effect of anti-reflux treatment on gastroesophageal reflux-associated chronic cough: implications of neurogenic and neutrophilic inflammation. J Asthma. 2020; 57: 1202-1210. doi: 10.1080/02770903.2019.1641204.
  10. Hagiwara H, Fukuta H, Niimura T, Zamami Y, Ishizawa K, Kimura K, Kamiya T, Ohte N. Comparison of Hemorrhagic Risk between Prasugrel and Clopidogrel: a Retrospective Study using Adverse Drug Event Reporting Databases. Int J Med Sci.2020;17:728-733
  11. Venkatesan S, Myles PR, Bolton KJ, Muthuri SG, Al Khuwaitir T, Anovadiya AP, Azziz-Baumgartner E, Bajjou T, Bassetti M, Beovic B, Bertisch B, Bonmarin I, Booy R, Borja-Aburto VH, Burgmann H, Cao B, Carratala J, Chinbayar T, Cilloniz C, Denholm JT, Dominguez SR, Duarte PAD, Dubnov-Raz G, Fanella S, Gao Z, Gérardin P, Giannella M, Gubbels S, Herberg J, Higuera Iglesias AL, Hoeger PH, Hu XY, Islam QT, Jiménez MF, Keijzers G, Khalili H, Kusznierz G, Kuzman I, Langenegger E, Lankarani KB, Leo YS, Libster RP, Linko R, Madanat F, Maltezos E, Mamun A, Manabe T, Metan G, Mickiene A, Mikić D, Mohn KGI, Oliva ME, Ozkan M, Parekh D, Paul M, Rath BA, Refaey S, Rodríguez AH, Sertogullarindan B, Skręt-Magierło J, Somer A, Talarek E, Tang JW, To K, Tran D, Uyeki TM, Vaudry W, Vidmar T, Zarogoulidis P; PRIDE Consortium Investigators, Nguyen-Van-Tam JS. Neuraminidase Inhibitors and Hospital Length of Stay: A Meta-analysis of Individual Participant Data to Determine Treatment Effectiveness Among Patients Hospitalized With Nonfatal 2009 Pandemic Influenza A(H1N1) Virus Infection. J Infect Dis. 2020;221(3):356-366. doi: 10.1093/infdis/jiz152.
  12. Kada A, Fukano R, Mori T, Kamei M, Tanaka F, Ueyama J, Sekimizu M, Osumi T, Mori T, Koga Y, Ohki K, Fujita N, Mitsui T, Saito AM, Hashimoto H, Kobayashi R. A multicenter, open-label, clinical trial to assess the efficacy and safety of allogeneic hematopoietic stem cell transplantation using reduced-intensity conditioning in relapse/refractory anaplastic large-cell lymphoma in children. Acta Med Okayama. 2020;74:89-94.
  13. Goto T, Mori K, Nakasuka K, Kato M, Nakayama T, Banno T, Ichihashi T, Wakami K, Fukuta H, Seo Y, Ohte N. Physical activity and mortality in older patients with a pacemaker. Geriatr Gerontol Int. 2020;20:106-111.